Women's Plus Size Button Up Shirts

Dress to the nines in our chic button up shirts, perfect for smart casual affairs. A true wardrobe staple, every woman needs a stylish selection of shirts to choose from, whether it's a bold printed pick or classic white shirt. From desk-to-dinner, Avenue ensures all of your style needs are sorted.

  1. Longline Blouse - black diamond
    Regular Price $69.99 As low as $21.00
    Brushed Diamond
    Red Fleck
    70% OFF*
  2. Longline Blouse - red fleck
    Regular Price $69.99 As low as $21.00
    Brushed Diamond
    Red Fleck
    70% OFF*
  3. Kylee Plaid Shirt - sangria
    Regular Price $69.99 As low as $19.99
    Mocha
    Sangria
    $19.99* SHIRTS
  4. Aspen Plain Shirt - black
    Regular Price $69.99 As low as $21.00
    70% OFF*
  5. Presley Print Shirt - mono check
    Regular Price $69.99 As low as $21.00
    Animalia
    Check Mate
    Mono Scatter
    70% OFF*
  6. Longline Print Blouse - black red
    Regular Price $69.99 As low as $19.99
    Black/red Geo
    Navy/teal Geo
    Plum/spice Geo
    $19.99* SHIRTS
  7. Fly Away Shirt - black
    Regular Price $69.00 As low as $34.50
    50% OFF*
  8. Longline Print Blouse - plum
    Regular Price $69.99 As low as $19.99
    Black/red Geo
    Navy/teal Geo
    Plum/spice Geo
    $19.99* SHIRTS
  9. Isadora Top - black
    Regular Price $69.00 As low as $34.50
    50% OFF*
  10. Longline Print Blouse - navy
    Regular Price $69.99 As low as $19.99
    Black/red Geo
    Navy/teal Geo
    Plum/spice Geo
    $19.99* SHIRTS
  11. Relaxed Summer Shirt - teal
    Regular Price $65.00 As low as $32.50
    Jungle
    Mocha
    Teal
    50% OFF*
  12. Aspen Print Shirt - black
    Regular Price $69.99 As low as $21.00
    70% OFF*
  13. Kylee Check Shirt - jade
    Regular Price $65.99 As low as $19.80
    Berry
    Jade
    70% OFF*
  14. Roxy Shirt - black
    Regular Price $69.99 As low as $24.00
    $24* SHIRTS
  15. Kylee Check Shirt - berry
    Regular Price $65.99 As low as $19.80
    Berry
    Jade
    70% OFF*
  16. Relaxed Summer Shirt - jungle
    Regular Price $65.00 As low as $32.50
    Jungle
    Mocha
    Teal
    50% OFF*
  17. Luxe Embroidered Tunic - moss
    Regular Price $69.99 As low as $35.00
    50% OFF*
  18. Tropical Tie Top - ivory
    Regular Price $69.00 As low as $34.50
    50% OFF*
  19. Enchant Tunic - crimson
    Regular Price $69.00 As low as $19.99
    $19.99* SHIRTS
  20. Sabine Shirt - black
    Regular Price $69.00 As low as $34.50
    Black
    Ivory
    50% OFF*
  21. Sophia Shirt - seafoam
    Regular Price $69.00 As low as $34.50
    Black Festival B
    Seafoam Festival B
    50% OFF*
  22. Sabine Shirt - ivory
    Regular Price $69.00 As low as $34.50
    Black
    Ivory
    50% OFF*
  23. Pleat Zip Print Blouse - black
    Regular Price $59.99 As low as $18.00
    70% OFF*
  24. Eastbrook Plain Top - chestnut
    Regular Price $69.99 As low as $19.99
    $19.99* SHIRTS
  25. Emily Shirt - black
    Regular Price $69.00 As low as $34.50
    50% OFF*
  26. Sophia Shirt - black
    Regular Price $69.00 As low as $34.50
    Black Festival B
    Seafoam Festival B
    50% OFF*
  27. Diamond Affair Top - ivory
    Regular Price $69.00 As low as $34.50
    50% OFF*
  28. Kylee Plaid Shirt - mocha
    Regular Price $69.99 As low as $19.99
    Mocha
    Sangria
    $19.99* SHIRTS
  29. Anthea Shirt - black
    Regular Price $69.00 As low as $34.50
    50% OFF*
  30. Teresa Pleat Shirt - neutral
    Regular Price $79.99 As low as $40.00
    Earn Your Stripes
    Wild Beauty
    50% OFF*
  31. Relaxed Summer Shirt - mocha
    Regular Price $65.00 As low as $32.50
    Jungle
    Mocha
    Teal
    50% OFF*
  32. Teresa Pleat Shirt - neutral stripes
    Regular Price $79.99 As low as $40.00
    Earn Your Stripes
    Wild Beauty
    50% OFF*
  33. Roxy Print Shirt - black noise
    Regular Price $69.99 As low as $24.00
    $24* SHIRTS
  34. Trail Blazer Shirt - light wash
    Regular Price $69.00 As low as $34.50
    50% OFF*
  35. Blue Spot Shirt - blue
    Regular Price $69.00 As low as $34.50
    50% OFF*
  36. Liana Lace Blouse - bluebird
    Regular Price $69.99 As low as $19.99
    Bluebird
    Merlot
    $19.99* SHIRTS
  37. Check Shirt - black
    Regular Price $65.99 As low as $19.80
    70% OFF*
  38. Gathered Waist Tunic - navy spot
    Regular Price $69.00 As low as $19.99
    Navy/white Spot
    Spot
    $19.99* SHIRTS
  39. Popover Blouse - neutral
    Regular Price $59.99 As low as $19.99
    Catalina Floral
    Quant Mono
    $19.99* SHIRTS
  40. Celeste Longline Print Shirt - teal chevron
    Regular Price $69.99 As low as $19.99
    Between The Lines
    Mission Zig Zag
    $19.99* SHIRTS
  41. Sophia Shirt - ivory
    Regular Price $69.99 As low as $35.00
    50% OFF*

Dress smart in our women's plus size button up shirts, perfect for office styling and casual days alike. These fashion-forward picks feature collared necklines and relaxed silhouettes, as well as a number of prints, hues and cuts to choose from. Whatever you need, shop Avenue.com for endless style.